This course examines the nature, ends, and practice of medicine as it relates to the human condition. How can medicine foster human flourishing and well-being—individual and social—against the experience of injury, pain, and suffering? Beginning with ancient Greece and its Hippocratic corpus, students explore answers to this question within a variety of historical and contemporary contexts. Taught by an interdisciplinary team of scholars that includes medical professionals, the course highlights the importance and professional relevance of posing big questions about personal meaning and human values at stake in the practice of medicine.